PMS1 Polyclonal Antibody, 100ul Deep Well Plates Two alternatively spliced transcript variants
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PMS1 Polyclonal Antibody, 100ul Deep Well Plates Two alternatively spliced transcript variantsPMS1 encodes a protein belonging to the DNA mismatch repair mutL hexB family. PMS1 homolog 1, mismatch repair system component is thought to be involved in the repair of DNA mismatches, and it can form heterodimers with MLH1, a known DNA mismatch repair protein. Mutations in PMS1 cause hereditary nonpolyposis colorectal cancer type 3 (HNPCC3) either alone or in combination with mutations in other genes involved in the HNPCC phenotype, which is also
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