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One peptide-receptor event can activate many downstream proteins, leading to a measurable change in hormone output

Human trials are still small

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PAX-D was the largest clinical trial to date into Pramipexole, a drug usually used for Parkinson's, for treatment resistant depression

To minimize the risk of drug interactions, it is important to inform your healthcare provider of all medications you are currently taking, including over-the-counter drugs, supplements, and herbal products