Neuro D Polyclonal Antibody, 50ul Measuring Instruments The N-terminal region of the

The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity| indicating a role as a negative regulator of CDC2/cyclin A

Although the active site residues are conserved

Ubiquitin-like modifier-activating enzyme 5 activates ubiquitin-fold modifier 1

key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol

Allelic variations at amino acid positions 654 and 655 of isoform a (positions 624 and 625 of isoform b) have been reported

Neuro D Polyclonal Antibody, 50ul Measuring Instruments The N-terminal region of theNEUROD1 encodes a member of the NeuroD family of basic helix loop helix (bHLH) transcription factors. The protein forms heterodimers with other bHLH proteins and activates transcription of genes that contain a specific DNA sequence known as the E box. It regulates expression of the insulin gene, and mutations in this gene result in type II diabetes mellitus.