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Biochemistry 56:20102023

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Epidemiology and pathophysiology of heart failure As one of the most prevalent consequences of CVD and other cardiometabolic conditions such as diabetes and hypertension, HF remains associated with high mortality rates ( As outlined earlier, cardiometabolic diseases or risk factors such as type 2 diabetes (Nichols et al., 2004), obesity (Powell-Wiley et al., 2021) and hypertension (Oh and Cho, 2020) are major predictors for HF

however, the impact of targeting pyroptosis is less clear