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Furthermore, response to both internal and external stimuli such as pH gradients, reducing agents, ROS, electric field, temperature, and NIR radiation, which have been researched numerously, was debated

It wouldnt surprise me that improving peoples health this way actually slows down the ageing process. The studies were produced from the Select trial in the US, which studied 17,604 people aged 45 or older who were overweight or obese and had established cardiovascular disease but not diabetes

This concept offers the possibility of selecting the signaling pathway, which will have an increased therapeutic effect, while the undesired downstream signal cascades and consequent side-effects could be minimalized [81]