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This is not a direct side effect of the drug itself, but rather a consequence of losing weight quickly

Based on the full population pharmacokinetic model, values for CL/F and V/F in the reference subject profile were estimated to be 0.0478 l/h and 12.2 l, respectively (Table S3 in the ESM)

If you're pregnant, breastfeeding or trying to conceive, berberine isn't recommended because there isn't enough safety data

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