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Because your skeletal muscles are filled with mitochondria (the portion of your cell responsible for energy production in your body) and we know that B12 directly acts in these mitochondria

The rats treated with BPC 157 exhibited resolved tail spasticity by day 15 post-injury while the rats in the control group did not exhibit sustained spasticity until day 360 [3]

1 H NMR (400 MHz, DMSO) 8.74 (s, 1H), 8.22 (d, J = 8.3 Hz, 1H), 7.50 7.39 (m, 9H), 7.22 (s, 1H), 7.18 7.09 (m, 6H), 6.91 (t, J = 6.0 Hz, 1H), 4.57 (td, J = 9.0, 4.8 Hz, 1H), 3.50 (d, J = 10.9 Hz, 2H), 3.14 (dd, J = 15.0, 4.9 Hz, 1H), 2.94 (dd, J = 15.0, 9.8 Hz, 1H), 1.34 (s, 9H)

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Toxicol Lett 245:7885 Kim J-H, Baek J-I, Lee I-K, Kim U-K, Kim Y-R, Lee K-Y (2022) Protective effect of berberine chloride against cisplatin-induced ototoxicity