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Post-translational processing of POMC into mature -MSH necessitates well-coordinated actions of several enzymes including carboxypeptidase E (CPE) and -amidating monooxygenase (PAM), which co-localize in POMC-expressing cells (Cawley et al, 2016)

Therefore researchers recommend more studies are needed on how B12 may affect weight

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Estos efectos sobre la conducta alimentaria se deben a la interaccin con reas del cerebro como el hipotlamo y el sistema lmbico, que son cruciales en la regulacin del apetito y las emociones

This dysbiotic state, strongly promoted by a HFD, compromises the intestinal mucus layer and weakens tight junction integrity, leading to increased intestinal permeability (leaky gut) (90, 93, 94)

Lipoic acid also contains an asymmetric carbon, which means that lipoic acid can exist as one of two possible optical isomers, also called enantiomers