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JAMA 2014;311:2297-304

Association between Metformin and a Lower Risk of Age-Related Macular Degeneration in Patients with Type 2 Diabetes

Southwest Family Medical

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BPC 157 was successful in the therapy of GI tract, periodontitis, liver and pancreas lesions, and in the healing of various tissues and wounds

however, it negatively affected the fetal weight, yet it was considered negligible due to liraglutides known effect of suppressing appetite ( As GLP-1 agonists have garnered attention for management of obesity due to their effect on reducing insulin sensitivity, they are now being considered a therapeutic option for the treatment of PCOS (polycystic ovarian syndrome), one of the most common causes of subfertility, diagnosed via Rotterdams criteria: oligomenorrhea, hyperandrogenism and polycystic ovaries ( A comparative study conducted between GLP-1RA + Metformin in contrast to cyproterone acetate/ethinylestradiol + Metformin in overweight PCOS women, conducted over a period of 12 weeks, implied that GLP-1 RA+Metformin was superior in reducing the waist circumferences as well as preserving blood sugar levels by improved HbA1c levels and regulating menstrual cycle