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The effects of myo-inositol and D-Chiro-inositol in a ratio 40: 1 on hormonal and metabolic profile in women with polycystic ovary syndrome classified as phenotype a by the Rotterdam criteria and EMS-Type 1 by the EGOI criteria

5.5 Conclusion and future direction Recognizing the limitations of conventional delivery routes in targeting the CNS, IN administration provides a non-invasive alternative that not only bypasses the BBB but also avoids hepatic first-pass metabolism