RILP Polyclonal Antibody, 100ul Virus Packaging DNA pol δ and DNA

DNA pol δ and DNA pol e are multisubunit enzymes

while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer

Members of this family have highly conserved secondary structures with a reactive center loop that interacts with the protease active site to inhibit protease activity

The protein encoded by this gene localizes to the nucleolus

Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane

RILP Polyclonal Antibody, 100ul Virus Packaging DNA pol δ and DNAThis gene encodes a lysosomal protein that interacts with RAB7, a small GTPase that controls transport to endocytic degradative compartments. Studies using mutant forms of the two proteins suggest that this protein represents a downstream effector for RAB7, and both proteins act together in the regulation of late endocytic traffic. A unique region of this protein has also been shown to be involved in the regulation of lysosomal morphology.