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Institute for Functional Medicine(IFM) The academic home of functional medicine

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Combining semaglutide, which is a GLP-1 receptor agonist, with cagrilintide, this long-acting amylin analog, may improve weight control and glycemic control in patients with type 2 diabetes. Combination therapy linked to more than 15% weight loss Juan P

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9,10 The mechanism of the relationship is poorly understood, with hypotheses including that a drop in blood sugar can lead to a rise in VEGF expression 11,12 and that systemic glycemic changes can correspond with glucose concentration in the vitreous, and in turn lead to retinal injury