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TP0463518 Catalog No.:M7516-10 and/or liver cell necrosis

SKU: 78327525940

4.6
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TP0463518 Catalog No.:M7516-10 and/or liver cell necrosisTP0463518 is a potent hypoxia inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5. 3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. Product information CAS Number: 1558021 37 6 Molecular Weight: 431. 83 Formula: C20H18ClN3O6 Chemical Name: (1 ((6 (4 chlorophenoxy)pyridin 3 yl)methyl) 4 hydroxy 2 oxo 1, 2, 5, 6 tetrahydropyridine 3 carbonyl)glycine Smiles:

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Description

and/or liver cell necrosis

and the inhibition of USP14 is more pronounced

PMID: 31792121

60:180-186

1159/000445589

TP0463518 Catalog No.:M7516-10 and/or liver cell necrosisTP0463518 is a potent hypoxia inducible factor prolyl hydroxylases (PHDs) inhibitor with Ki of 5. 3 nM for human PHD2. TP0463518 inhibits human PHD1, human PHD3 and monkey PHD2 with IC50 of 18 nM, 63 nM and 22 nM, respectively. Product information CAS Number: 1558021 37 6 Molecular Weight: 431. 83 Formula: C20H18ClN3O6 Chemical Name: (1 ((6 (4 chlorophenoxy)pyridin 3 yl)methyl) 4 hydroxy 2 oxo 1, 2, 5, 6 tetrahydropyridine 3 carbonyl)glycine Smiles:

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