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But without long-term human data, we must be cautious

Lowered A1C of 1.7%2.0% across doses Weight loss of 16.8% in the highest dose over 40 weeks without evidence of weight loss plateau The longer duration 80-week TRIUMPH-2 will more effectively evaluate the weight loss potential of retatrutide in those with type 2 diabetes and obesity, expected to result later this year Press release: investor.lilly.com/news-releases/ Dear colleague @MWeintraubMD

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Strathe A, Horn DB, Larsen MS, Rubino D, Srrig R, Tran MTD, Wharton S, Overgaard RV

Our findings are consistent with previous studies showing additional metabolic-cardiovascular-renal benefits of combined GLP-1RA and SGLT2i use in patients with T2D 26 , and suggest a promising role for adding GLP-1RA to SGLT2i therapy in patients with MASLD

A doctor can help determine whether the medication plan needs adjustment or whether other factors are affecting progress