semaglutide and sleep issues GLP-1s Sleep?: How and Why Do GLP-1s Affect Sleep? Semaglutide Fatigue: Feeling Weak on

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Wenjing et al

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Most patients notice some appetite reduction within the first few days of treatment, though the most significant effects appear gradually as the dose is titrated upward

One is by up-regulating a signaling protein called VEGF (vascular endothelial growth factor), which encourages the growth of new capillaries