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Answer the main query directly near the top, then expand with examples and caveats

Potential adverse effects such as weight gain [147], dyslipidemia, and increased risk of cerebrovascular and cardiovascular morbidity [148] are significant concerns

Patients who show an early positive response to GLP-1 receptor agonist therapy tend to have significantly better long-term adherence and are less likely to discontinue treatment compared to those who dont see quick results

The epoxyallylic radical intermediate is a precursor for further oxylipins, and for example, it can be converted by an epoxyalcohol synthase into an epoxyhydroxy fatty acid (allene oxides result from a separate enzymic reaction)

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However, the medication's profound metabolic effects create an indirect hormonal cascade that may influence reproductive health