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A 2017 study by Hsieh and colleagues in Journal of Molecular Medicine reported that BPC-157, in chick chorioallantoic membrane, rat hind-limb ischemia, and HUVEC models, directionally increased vessel density, accelerated blood-flow recovery in ischemic muscle, and time-dependently activated the VEGFR2-Akt-eNOS signaling pathway via VEGFR2 internalization a mechanistic preclinical finding for which numeric effect sizes are not reported in the abstract

Potential risks from improper use are unknown, as clinical data in humans are unavailable

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a urological tumor attributed to BPC-157 by the treating urologist after 5 months of use at 5 mg/day

The peptide has been found to speed up the process of healing wounds in the tissues, increasing the rate of growth in new blood vessels and helping to repair the gastrointestinal tract while also protecting other internal organs, such as the liver and brain