FBX46 Rabbit Polyclonal Antibody, 100ul Molecular Biology Apoptosis is related to many

Apoptosis is related to many diseases and induced by a family of cell death receptors and their ligands

This gene encodes glucose-6-phosphate dehydrogenase

Defects in PEX7 cause peroxisome biogenesis disorders (PBDs)

GO annotations related to this gene include G-protein coupled receptor activity and chemokine receptor activity

May be a negative regulator of NF-kappa-B and p53-mediated gene transcription

FBX46 Rabbit Polyclonal Antibody, 100ul Molecular Biology Apoptosis is related to manyMembers of the F box protein family such as FBXO46 are characterized by an approximately 40 amino acid F box motif. SCF complexes formed by SKP1 (MIM 601434) cullin (see CUL1; MIM 603134) and F box proteins act as protein ubiquitin ligases. F box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains (Jin et al. 2004