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Creams: Lower peptide concentration (0.11%) but increased contact time

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TB-500 then supports the migration of regenerative progenitor cells into the damaged zone, reorganizes the cytoskeletal matrix, and drives remodeling of collagen architecture that determines long-term structural recovery

Criteria for necrosis included karyorrhexis (loss of nucleus) and/or degeneration of cytoplasm with either coagulative or liquefactive changes

All of the studies used both in vivo and some form of in vitro methods of data collection in order to observe different treatment effects, allowing for biomechanical, functional (use of AFI index and load to failure), macroscopic and microscopic histological analysis