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Beyond their role in weight reduction, which itself can lessen mechanical friction and inflammation in intertriginous areas, GLP-1s improve insulin sensitivity, cardiometabolic risk factors, and may reduce systemic inflammationall of which can be more prevalent in HS patients

Key indicators of this transformation include trends in medtech volumes, such as a decline in bariatric surgeries, shifts in insurers policies and early adoption of oral obesity medications

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However, the final answer depends on the employers selected benefit design

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10 Anti-Inflammatory Signaling: These agents inhibit pro-inflammatory pathways (NF-B and MAPK) in vascular smooth muscle cells, reducing cytokines like IL-6 and TNF-