CL-387785 - CAS# 194423-06-8 60102 GSK269962 can become an alternative

GSK269962 can become an alternative worth considering in OAB treatment

is a natural substance

CAS Number: 3650-09-7

28)19-9-14-15(10-17(19)29-7-6-26)22-11-23-20(14)25-13-4-5-18-16(8-13)24-12-30-18/h4-5

Smiles: CC(O)(CN1C=NC=N1)C1=CC=C(C=C1C(F)(F)F)OC1C=CC(Cl)=CC=1

CL-387785 - CAS# 194423-06-8 60102 GSK269962 can become an alternativeCL 387785, CAS No. 194423 06 8, also known as EKI 785 , is a n irreversible inhibitor of EGF receptor (EGFR) kinase activity in vivo (IC50 = 250 490 pM). CL 387785 covalently bound to EGF R. It also specifically inhibited kinase activity of the protein (IC50 = 370+ 120 pM), blocked EGF stimulated autophosphorylation of the receptor in cells (ic50 approximately 5 nM), inhibited cell proliferation (IC50 = 31 125 nM) primarily in a cytostatic manner in