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doi: 10.1016/j.cell.2022.11.020 197 von StreitbergA.JkelS.Eugenin von BernhardiJ.StraubeC.BuggenthinF.MarrC.et al

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doi:10.1074/jbc.271.24.14119

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Manzari MT, Shamay Y, Kiguchi H, Rosen N, Scaltriti M, Heller DA (2021) Targeted drug delivery strategies for precision medicines

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It is shown that IGFBP1 expression and secretion were significantly elevated in cancer cells, and secreted IGFBP-1 inhibits AKT1-mediated phosphorylation of ser27 of mitochondrial superoxide dismutase 2 (SOD2), thereby increasing the activity of SOD2 antioxidant enzymes

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