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FIGURE 2 Effect of Multi-Copy sod- Expression Cassettes in S

(4) Furthermore, the oxidative stress imbalance, caused by excessive ROS production, impairs the antioxidant defense system by directly damaging antioxidant enzymes (such as SOD and GPx) and depleting key antioxidant molecules like glutathione, leading to fragmentation of hyaluronic acid in the extracellular matrix and abnormal collagen cross-linking, thereby reducing the mechanical properties of cartilage (6, 22, 23)

As well as hydrolysates from milk and bean protein, in in vivo models hydrolysate from the egg protein lysosyme has also shown a 25 % reduction in blood serum DPP4 activity and a trend towards higher serum GLP-1 levels after 90 min in diabetic rats undergoing chronic treatment (Reference Wang, Landheer and van Gilst100)

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It should be avoided in these patients

This finding has significant implications: it suggests that the cancer-protective effects of GLP-1 therapy extend substantially beyond weight reduction alone, implicating independent biological mechanisms