SmcX Monoclonal Antibody, 100ul Reagent Reservoirs Both N- and C-terminal domains

Both N- and C-terminal domains are required for transcriptional activation

PEA15 (phosphoprotein enriched in astrocytes 15) encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis

Overexpression of CAGE leads to the activation of FAK

Among its related pathways are Gene Expression and tRNA processing

NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells

SmcX Monoclonal Antibody, 100ul Reagent Reservoirs Both N- and C-terminal domainsThis gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD type zinc fingers. The DNA binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X linked mental retardation. Alternative splicing results in multiple transcript variants.