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Description

As a key methyltransferase of m6A, METTL3 can inhibit the activation of pTHP-1 macrophages by preventing the generation of IL-6 and TNF-, and attenuate inflammatory response induced by LPS via the NF-B signaling pathway (178)

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Huot JR, Baumfalk D, Resendiz A, Bonetto A, Smuder AJ, Penna F (2023) Targeting mitochondria and oxidative stress in cancer-and chemotherapy-induced muscle wasting