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Additionally, measures of endothelial function improved, blood pressure (both systolic and diastolic) was reduced and markers of inflammation were more favorable

Meanwhile, studies have shown that bile acids can affect the intestinal epithelial barrier through receptor signaling pathways (FXR/TGR5) (Cipriani et al., 2011

The improvement comes through weight loss and metabolic improvement

"Serum steroids in relation to benign prostatic hyperplasia"

While a significant number of people taking a GLP-1 who posted experienced fatigue, its not clear how many comparable people not taking a GLP-1 would also report that symptom