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SQSTM1/p62 Rabbit Polyclonal Antibody, 50ul Micro Centrifuge Tubes Mutations in this gene could

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SQSTM1/p62 Rabbit Polyclonal Antibody, 50ul Micro Centrifuge Tubes Mutations in this gene couldThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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Description

Mutations in this gene could be involved in the malignant progression of colon cancer

Th1 cells are involved in cell-mediated immunity to intracellular pathogens and delayed-type hypersensitivity reactions

and two pseudogenes of this gene are also located on the long arm of chromosome 9

It functions in filopodia formation

The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB)

SQSTM1/p62 Rabbit Polyclonal Antibody, 50ul Micro Centrifuge Tubes Mutations in this gene couldThis gene encodes a multifunctional protein that binds ubiquitin and regulates activation of the nuclear factor kappa B (NF kB) signaling pathway. The protein functions as a scaffolding adaptor protein in concert with TNF receptor associated factor 6 to mediate activation of NF kB in response to upstream signals. Alternatively spliced transcript variants encoding either the same or different isoforms have been identified for this gene. Mutations in

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