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How ROSE-010 Works in IBS: Targeted, On-Demand Pain Relief ROSE-010 mimics natural GLP-1 with an optimized, short-acting profile: Fast-acting ( Begins working in 20 minutes ) Short duration ( Clears in a few hours ) Use only when needed during acute episodes for pain resolution Clinical Validation: Proven IBS Pain Relief In Phase 2a Trial Results (Hellstrm et al.), ROSE-010 166 patients with IBS pain (placebo-controlled study) Twice as many patients responded to ROSE-010 vs

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developed a smaller enzyme called BioID2 with a molecular weight of 27 kDa, derived from Aquifex aeolicus [16]

Insert the needle at a 45 to 90-degree angle into the pinched skin

doi: 10.3920/WMJ2010.1244 83 MossM