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Metabolic Syndrome GLP-1 therapy supports better metabolism, lower inflammation, and reduced risk factors associated with metabolic syndrome

Gustafson H, Johansson B, Edsmyr F

Notably, it leads to a substantial reduction in the prevalence of the Proteobacteria phylum and the Gammaproteobacteria class, in turn diminishing gut inflammation

In the phase 2 trial published in The Lancet (2023), adults with type 2 diabetes receiving the 12 mg dose of retatrutide achieved a mean body weight reduction of approximately 16.9% from baseline at 24 weeks

Additionally, interactions with anticoagulants or thyroid

[62] these functional impairments involve impaired dopamine neurotransmission in the mesocorticolimbic projection and norepinephrine neurotransmission in the noradrenergic projections from the locus coeruleus to the prefrontal cortex