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At the cell cluster level (clustered within tissue type), females tended to express modestly higher levels of GLP1R mRNA when compared to the same tissues from males, a difference that in several clusters achieved statistical significance (Fig

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Recent findings indicate that the anti-inflammatory effects of GLP-1RAs, mediated through GLP-1R in CNS neurons (268) and intrahepatic lymphocytes (269), play an important role in their antiatherogenic actions

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Multimodal physical therapy programs that combine muscle training, education, and physical activity have also shown strong improvements in symptoms and quality of life, with high patient satisfaction and no reported safety concerns