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ROS1 Polyclonal Antibody, 20ul Shaker&Mixing Increased expression of this gene

SKU: 16846146540

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ROS1 Polyclonal Antibody, 20ul Shaker&Mixing Increased expression of this geneThis proto oncogene, highly expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.

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Description

Increased expression of this gene in colorectal tumors and colon polyps compared to matched normal colonic mucosa has been observed

and later in life by skeletal myopathy or cardiomyopathy

Alternative splice variants have been described but their full-length sequence has not been determined

PAI-1 and PAI-2 regulate uPA (urokinase-type plasminogen activator) and TPA (tissue plasminogen activator)

Probably involved in the function of nociceptive neurons

ROS1 Polyclonal Antibody, 20ul Shaker&Mixing Increased expression of this geneThis proto oncogene, highly expressed in a variety of tumor cell lines, belongs to the sevenless subfamily of tyrosine kinase insulin receptor genes. The protein encoded by this gene is a type I integral membrane protein with tyrosine kinase activity. The protein may function as a growth or differentiation factor receptor.

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