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and (ii) the indiscriminate substitution of industrialized products already available and approved by ANVISA

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In the Phase 3 TRIUMPH-1 trial in adults with obesity (without type 2 diabetes), the highest studied dose was associated with an average weight loss of about 28.3% at 80 weeks roughly 70 pounds reaching about 30.3% at 104 weeks, and about 45% of participants lost at least 30% of their body weight

FDA data suggest that those taking tesamorelin have about three times higher odds of developing diabetes

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