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This is a temporary shedding phase caused by the caloric deficit and weight change, not by tirzepatide directly

Additionally, previous literature has identified various mechanisms of action for the aforementioned compounds, which disrupt membranes and nucleic acid synthesis, ultimately reducing extracellular polymeric substance secretion and the formation of biofilms 100

Affiliation: 2 Department of Endocrinology, Changi General Hospital, Singapore 529889, Singapore 3 Medicine Academic Clinical Program, Duke-NUS Graduate Medical School, Singapore 169857, Singapore ORCID: Affiliation: 4 Department of Laboratory Medicine, Changi General Hospital, Singapore 529889, Singapore 5 Pathology Academic Clinical Program, Duke-NUS Graduate Medical School, Singapore 169857, Singapore 6 Yong Loo Lin School of Medicine, National University of Singapore (NUS), Singapore 119228, Singapore Email: [email protected] ORCID: Explor Endocr Metab Dis