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Notably, wild-type TTR is also associated with amyloidosis and is predominantly linked to cardiac manifestations [4]

doi: 10.1186/s12859-018-2085-6 62 ZhaoHWuWLiXChenW

In human bronchial epithelial cells, exposure to H 2 O 2 induced IL-8 synthesis in a concentration-dependent manner as a result of mitogen-activated protein kinase, which is responsible for IL-8 mRNA stability and expression (Pelaia et al., 2004

& Lewis, R

Therefore, formulating stable and bioactive macromolecules in transdermal delivery systems requires careful consideration of excipients, storage conditions, and manufacturing processes [51]

However, a considerable part of patients presents with unsatisfactory response in the long term

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