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Compr Physiol 11431211 Zeng Q, Li N, Pan X-F, Chen L, Pan A (2021) Clinical management and treatment of obesity in China

Flodstrom-Tullberg M

Taken together, the present findings suggest CD38 as an immunometabolic checkpoint that could be adopted as a pre-symptomatic biomarker for early diagnosis of AD, and might also be therapeutically targeted alone or in combination with other immunotherapies for disease modification

This gradual escalation minimizes gastrointestinal adverse effects such as nausea, vomiting, and diarrhea, which are the most common reasons for treatment discontinuation