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The CB4211 trial produced statistically significant improvements in liver enzymes and fasting glucose in humans

104 Many other animal studies have reported similar antidepressant-like effects with GLP-1 receptor agonists

One inpatient diagnosis, or 2 different outpatient encounter diagnoses were required to meet criteria for a respective event (see list in Supplementary Table S9).We extracted date of death from the VHA Death Ascertainment File which contain mortality data from the Master Person Index file in CDW and the Social Security Administration Death Master File

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