p53 Polyclonal Antibody, 100ul[BT-AP06814] Recombinant Protein Expression Binds to the proximal sequence

Binds to the proximal sequence element (PSE)

This protein is also a p53-regulated neurogenic factor involved in p53 dependent neuronal differentiation

and may contribute to the antiviral activity of CD8(+) T-cells

The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins

2002 [PubMed 11836249])

p53 Polyclonal Antibody, 100ul[BT-AP06814] Recombinant Protein Expression Binds to the proximal sequenceTP53 (tumor protein p53) encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in TP53 are associated with a variety of human cancers, including hereditary cancers such as Li Fraumeni