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RUNX1 Polyclonal Antibody, 50ul[BT-AP08058] Gene Synthesis A chromosomal translocation involving this

SKU: 19763763193

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RUNX1 Polyclonal Antibody, 50ul[BT-AP08058] Gene Synthesis A chromosomal translocation involving thisCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three

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Description

A chromosomal translocation involving this gene on chromosome 17 and the MLL gene on chromosome 11 results in acute myelomonocytic leukemia

This RIN1-Ras interaction is enhanced when Ras is bound to GTP

Neuronal cell surface protein that may be involved in cell recognition and cell adhesion by forming intracellular junctions through binding to neuroligins

Mutations in TBX3 cause ulnar-mammary syndrome

These family members function in a protein kinase signal transduction cascade

RUNX1 Polyclonal Antibody, 50ul[BT-AP08058] Gene Synthesis A chromosomal translocation involving thisCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three

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