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If you apply a thick layer, the excess copper cannot absorb and will sit on the surface, leaving a temporary blue cast that washes off easily

The human evidence is limited, but the mechanistic rationale is enough that this remains an active research area

Researchers should note that layering GHK-Cu with strong vitamin C or retinol in combination formulations may alter peptide stability

The peptide's short half-life necessitates daily administration, preferably at consistent times to maintain stable plasma levels

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[7] It is advisable for patients to inform their healthcare provider of all medications and supplements they are taking, so that potential interactions can be monitored and managed appropriately