Human B-cell Linker Protein, BLNK ELISA Kit , 96T Mammalian Expression is generated in pathophysiologic conditions

is generated in pathophysiologic conditions such as inflammation

are involved in vescicle-mediated transport of proteins and lipids

It is highly similar to Saccharomyces cerevisiae Cdc14

This gene encodes a type I transmembrane protein and member of the immunoglobulin superfamily of cell adhesion molecules

ABCA13 is a member of ABC gene subfamily A (ABCA)

Human B-cell Linker Protein, BLNK ELISA Kit , 96T Mammalian Expression is generated in pathophysiologic conditionsFunctions as a central linker protein, downstream of the B cell receptor (BCR), bridging the SYK kinase to a multitude of signaling pathways and regulating biological outcomes of B cell function and development. Plays a role in the activation of ERK EPHB2, MAP kinase p38 and JNK. Modulates AP1 activation. Important for the activation of NF kappa B and NFAT. Plays an important role in BCR mediated PLCG1 and PLCG2 activation and Ca(2+) mobilization and