PGE synthase Polyclonal Antibody, 100ul Electronic Pipette The protein encoded by this

The protein encoded by this gene catalyzes the conversion of 5

Gene Ontology (GO) annotations related to this gene include G-protein coupled receptor activity and trace-amine receptor activity

Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease

It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel

This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF)

PGE synthase Polyclonal Antibody, 100ul Electronic Pipette The protein encoded by thisProstaglandin E synthase encoded by PTGES is a glutathione dependent prostaglandin E synthase. The expression of PTGES has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that PTGES may contribute to the pathogenesis of collagen induced arthritis and mediate acute pain