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AASS Polyclonal Antibody, 50ul DNA Fragments This gene encodes a protein

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AASS Polyclonal Antibody, 50ul DNA Fragments This gene encodes a proteinAASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.

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Description

This gene encodes a protein which interacts with the carboxy-terminus of the RAP74 subunit of transcription initiation factor TFIIF| and functions as a phosphatase that processively dephosphorylates the C-terminus of POLR2A (a subunit of RNA polymerase II)| making it available for initiation of gene expression

The encoded protein is a component of histone deacetylase-containing multiprotein complexes that function through modifying chromatin structure to keep genes silent

The yeast CDC10 protein is a structural component of the 10 nm filament which lies inside the cytoplasmic membrane and is essential for cytokinesis

SODs are antioxidant enzymes that catalyze the conversion of superoxide radicals into hydrogen peroxide and oxygen| which may protect the brain| lungs| and other tissues from oxidative stress

Genomic sequences representing several pseudogenes have been described and two transcript variants encoding different isoforms have been identified for this gene

AASS Polyclonal Antibody, 50ul DNA Fragments This gene encodes a proteinAASS encodes a bifunctional enzyme (aminoadipate semialdehyde synthase) that catalyzes the first two steps in the mammalian lysine degradation pathway. The N terminal and the C terminal portions of this enzyme contain lysine ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha aminoadipic semialdehyde. Mutations in AASS are associated with familial hyperlysinemia.

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