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DLEC1 Polyclonal Antibody, 50ul Pathway and Network Analysis This gene is a transcribed

SKU: 14867096609

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PLN162.00 PLN198.00

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DLEC1 Polyclonal Antibody, 50ul Pathway and Network Analysis This gene is a transcribedThe cytogenetic location of DLEC1 (deleted in lung and esophageal cancer 1) is 3p21. , and it is located in a region that is commonly deleted in a variety of malignancies. Down regulation of DLEC1 has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of DLEC1 in tumor cells is a result of aberrant promoter methylation. Several alternatively

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Description

This gene is a transcribed pseudogene belonging to the calcium sensitive chloride conductance protein family

This gene was demonstrated to be up-regulated by androgenic hormones in prostate cancer cells and down-regulated in androgen-independent prostate cancer tissue

Seems to negatively regulate the level of HIF1A expression

the N-terminal region contains a polyglutamine tract of 14-31 residues that can be expanded in the pathogenic state to 32-200 residues

POU class 2 homeobox 2 encoded by POU2F2 is a homeobox-containing transcription factor of the POU domain family

DLEC1 Polyclonal Antibody, 50ul Pathway and Network Analysis This gene is a transcribedThe cytogenetic location of DLEC1 (deleted in lung and esophageal cancer 1) is 3p21. , and it is located in a region that is commonly deleted in a variety of malignancies. Down regulation of DLEC1 has been observed in several human cancers including lung, esophageal, renal tumors, and head and neck squamous cell carcinoma. In some cases, reduced expression of DLEC1 in tumor cells is a result of aberrant promoter methylation. Several alternatively

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