p300 (Acetyl Lys1542) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The encoded protein interacts with

The encoded protein interacts with the hepatitis B virus X protein and plays a role in regulating hepatitis C virus internal ribosome entry site (IRES) activity| an activity essential for viral replication

This gene encodes a protein sharing a low level of sequence similarity with ribosomal protein P0

Mutations in this gene are associated with type II autosomal recessive Alport syndrome (hereditary glomerulonephropathy) and with familial benign hematuria (thin basement membrane disease)

The encoded protein also plays a role in the regulation of epidermal growth factor receptor turnover and actin remodelling

MTA1 (metastasis associated 1) encodes a protein that was identified in a screen for genes expressed in metastatic cells

p300 (Acetyl Lys1542) Polyclonal Antibody, 50ul Diagnostic Probes & Oligos The encoded protein interacts withThis gene encodes the adenovirus E1A associated cellular p300 transcriptional co activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co activator of HIF1A (hypoxia inducible factor 1