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MAN1B1 Polyclonal Antibody, 100ul Drug Development and Evaluation This protein and other members

SKU: 17386494700

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MAN1B1 Polyclonal Antibody, 100ul Drug Development and Evaluation This protein and other membersMAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N glycan biosynthesis, and is a class I alpha 1,2 mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N glycan trimming to Man5 6GlcNAc2 in the endoplasmic reticulum associated degradation pathway. Mutations in this gene cause autosomal recessive intellectual disability. Alternative splicing results in multiple

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Description

This protein and other members of the family are localized to synaptic vesicles and may function in the regulation of vesicle trafficking and exocytosis

PGBD1 belongs to the subfamily of piggyBac transposable element derived (PGBD) genes

This gene has a partial pseudogene on chromosome 1

resulting in hybrid cells that can generate both antibodies and proliferate indefinitely

The protein localizes to centrioles

MAN1B1 Polyclonal Antibody, 100ul Drug Development and Evaluation This protein and other membersMAN1B1 encodes an enzyme belonging to the glycosyl hydrolase 47 family. This enzyme functions in N glycan biosynthesis, and is a class I alpha 1,2 mannosidase that specifically converts Man9GlcNAc to Man8GlcNAc isomer B. It is required for N glycan trimming to Man5 6GlcNAc2 in the endoplasmic reticulum associated degradation pathway. Mutations in this gene cause autosomal recessive intellectual disability. Alternative splicing results in multiple

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