ARHGF Polyclonal Antibody, 20ul Adeno-associated Virus Packaging Mutations in this gene are

Mutations in this gene are a cause of cardiac septal defects

the gene is expressed in many tissues and exhibits a intracellular vesicular pattern in Panc-1 cells (pancreatic cancer cells)

and axial and limb hypotonia

Displays antiviral activity against influenza A virus by inhibiting the budding of the virus from the plasma membrane by disturbing the lipid rafts

PTM:May be sumoylated

ARHGF Polyclonal Antibody, 20ul Adeno-associated Virus Packaging Mutations in this gene areRho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. This gene encodes a protein that functions as a specific guanine nucleotide exchange factor for RhoA. It also interacts with ephrin A4 in vascular smooth muscle cells. Two alternatively spliced transcripts variants that encode the same protein have been found for this gene.