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PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing Contains 1 JmjC domain

SKU: 18326374942

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PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing Contains 1 JmjC domainThis gene encodes a cGMP binding, cGMP specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5' GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

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Description

Contains 1 JmjC domain

The encoded protein is a member of the junctional adhesion molecule protein family and acts as a receptor for another member of this family

a process whereby transcripts with premature termination codons are targeted for rapid degradation by a mRNA decay complex

An allelic variant encoding amino acid Lys at 915

This PTP has been shown to interact with

PDE5A Polyclonal Antibody, 50ul Immune Repertoire Sequencing Contains 1 JmjC domainThis gene encodes a cGMP binding, cGMP specific phosphodiesterase, a member of the cyclic nucleotide phosphodiesterase family. This phosphodiesterase specifically hydrolyzes cGMP to 5' GMP. It is involved in the regulation of intracellular concentrations of cyclic nucleotides and is important for smooth muscle relaxation in the cardiovascular system. Alternative splicing of this gene results in three transcript variants encoding distinct isoforms.

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