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RUNX1 Polyclonal Antibody, 100ul[BT-AP08059] Centrifuges which binds to the promoters

SKU: 18467556937

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RUNX1 Polyclonal Antibody, 100ul[BT-AP08059] Centrifuges which binds to the promotersCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three

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Description

which binds to the promoters of small nuclear and cytoplasmic RNA genes in order to recruit RNA polymerase III

Gene Ontology (GO) annotations related to NKX2-4 include sequence-specific DNA binding

trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR)

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one of which contains a clathrin-mediated trans-Golgi signal and an endoplasmic reticulum exit signal

RUNX1 Polyclonal Antibody, 100ul[BT-AP08059] Centrifuges which binds to the promotersCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by CBF2alpha (runt related transcription factor 1, RUNX1) represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three

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