Aquaporin 4 Monoclonal Antibody(4H1), 100ul Miscellaneous The BCL7A protein is encoded

The BCL7A protein is encoded by the gene known to be directly involved in a three-way gene translocation in a Burkitt lymphoma cell line

including one with a novel exon that is generated by RNA editing

Mutations in KAL1 cause the X-linked Kallmann syndrome

Recombination of these breakpoints results in the fusion of this gene and JAZF1

disease:A chromosomal aberration involving BCL6 may be a cause of a form of B-cell leukemia

Aquaporin 4 Monoclonal Antibody(4H1), 100ul Miscellaneous The BCL7A protein is encodedThis gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene