TMEM173 Polyclonal Antibody, 100ul Immune Cell Analysis which promotes its translocation to

which promotes its translocation to nuclear foci

and general transcription factors

Not essential for the survival of KRAS-dependent AML cell lines

thyroid follicular carcinomas and atypical follicular thyroid adenomas

it may regulate epithelial cell migration (PubMed: 23902688)

TMEM173 Polyclonal Antibody, 100ul Immune Cell Analysis which promotes its translocation toTMEM173 encodes a five transmembrane protein that functions as a major regulator of the innate immune response to viral and bacterial infections. The transmembrane protein 173 is a pattern recognition receptor that detects cytosolic nucleic acids and transmits signals that activate type I interferon responses. The encoded protein has also been shown to play a role in apoptotic signaling by associating with type II major histocompatibility complex.